Biohazard Cleaning

commercial cleaning

Commercial Cleaning

residential cleaning

Residential Cleaning

The Nitty-Gritty

Cleaning Services

  • Top-Bottom Deluxe Deep Clean
  • Post Construction/Remodel
  • Event Cleanup
  • Organization
  • Home Staging
  • Covid Sanitation
  • Holiday Cleanup
  • Move In/Move Out Cleanup

Specialized Cleaning Services

  • Sterilization
  • Blood Clean-Up
  • Urine And Feces Cleanup
  • Crime Scene and Trauma Cleanup
  • Biohazard Cleanup
  • Infectious Disease Cleanup
  • Medical Waste and Sharps Pickup
  • Lab Clean Up
  • Hoarding Cleanup
  • Industrial/Specialized Services
  • Terminal Cleaning
  • Certified Mold Remediation

About Us

We are a Christian-based company that strives for excellence and believes in compassion and integrity.

  • OSHA trained and Certified
  • Insured
  • References available
  • Affordable
  • Reliable
  • Dependable
  • On Call 24/7

We offer one-time cleaning services, or you can schedule recurring Weekly, Bi-weekly, or Monthly cleaning plans for your home or business at a very affordable price.

Call our team at Southern-Bio for a free estimate on your residential and office needs!

Now servicing Walker, Blount, Shelby, Jefferson, Cullman, St. Clair, and Winston Counties.

Our Reviews

Tim T.
Tim T.
Called Kristy and Sherry out for a deep clean after my toddlers wrecked the house. They did an awesome job... cleaning every nook and cranny. I recommend them for any and all cleaning more
Sarah B.
Sarah B.
We could not be more grateful for this cleaning team. They cleaned our home while we were away from home in... the hospital with a newborn. We came home to a spotlessly clean home with so many kind added touches. They even left a gift for the new baby. Not only is this team incredibly skilled in their cleaning regimen, but they are so friendly and flexible to work with. They even let our dog be in the home alone with them while we were away. 10/10 would recommend and can’t wait to use them again ourselves!read more
Debbie S.
Debbie S.
Southern Bio LLC have been a blessing. We first hired them for a move when we downsized after raising 4 kids... in a home for 23 years. They were able to clean and refresh cabinets, stair banisters, windows, windowsills, shower stalls, even dingy kids room walls that I thought would have to be repainted. They cleaned everything from top to bottom and left the house pristine. The house showed well and got a great price because of their great job. It was a two-story with a live-in basement.Because of their workmanship and excellence I have now hired them to come monthly to clean our home. Well worth your money. I’ve talked to friends who have hired other people who charged a lot more - a great more
William J.
William J.
These ladies saw that I was in a predicament per my last renter. They took one day of time to work for me. In... that time, they were successful in taking a destructive space and transitioning it ready-for-rent before the new month started. Grateful, and highly recommended!5-Stars ⭐️⭐️⭐️⭐️⭐️read more
Sarah G.
Sarah G.
Oh my goodness!! I cannot say enough good things about this company and these ladies!! I've had SEVERAL... cleaning services throughout the years and I always end up disappointed when I come home to a half cleaned house. Well, after recently having a baby and a husband stationed 3 hours away, I realized I needed help and reached out to these ladies via a Facebook post. I first had them deep clean our dog and cat room and it was BEAUTIFUL so I asked them to come back for a maintenance clean of the whole house. Y'all.... I am SPEECHLESS. It looks and smells SO GOOD in here that I don't even want to live here because I'm afraid of messing it up again!! These ladies have hearts of gold and an unmatched work ethic. I plan on using them FOREVER and I'm telling every momma I know about Southern Bio!! 💕💕💕read more
Kevin M.
Kevin M.
I was looking to have mold removed from my bathroom and closet and Southern Bio was recommended by someone... who was handling other work for me. They were prompt, communicative, patient, thorough and very respectful. They are also very competitive with their pricing.They did exactly what they said that they would do and I will recommend them to anyone looking to have this done.Thank you as it very difficult to find reputable companies like this right more
Connor R.
Connor R.
I have Southern Bio come periodically to clean my home and let me tell you there is no better cleaning... service in the area! They are attentive to every aspect of the home, fair with their pricing, and most important as professional as can be. I love coming home after work after they have come and cleaned. On top of that, when we had a Covid outbreak at the office earlier this year Southern Bio jumped into action to come and disinfect our office space so no one else would be at risk. Absolutely use these ladies for any of your cleaning needs!read more
Deirdre W.
Deirdre W.
These ladies came and cleaned my house and did a wonderful job! They were very friendly and very... professional. I would definitely recommend them to anyone who needs their house or business cleaned!read more
Mike Barnes (.
Mike Barnes (.
I can't say enough good things about this company. I have had them clean my home and my camper. They are... flexible and fantasticread more
Lisa M.
Lisa M.
These ladies do fabulous work. They are very professional and always show up on time. Reasonably priced and... great to work with!They completed a deep clean of our house and didn’t miss a single nook or cranny! We have them come every 2 weeks now for a maintenance clean and I love the house after they have been here. Everything is clean and smells more
Elizabeth T.
Elizabeth T.
They are ABSOLUTELY AMAZING! My house looks so good and smells AMAZING! Would definitely recommend them!!... There always on time great more


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